Description

N1-Methyl-3,5-Di(Trifluoromethyl)Aniline is a high-value fluorinated aromatic amine building block, distinguished by its unique trifluoromethyl substituents. This compound is essential for introducing lipophilicity, metabolic stability, and electron-withdrawing properties into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, central nervous system (CNS), and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl groups enhance biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic transformations.
• Functional Material Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers requiring specific electronic and solubility properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic pathway studies and imaging applications.

Basic Information

Product Name	N1-Methyl-3,5-Di(Trifluoromethyl)Aniline
CAS No.	42450-72-6
Molecular Formula	C9H7F6N
Molecular Weight	243.15 g/mol
Synonyms	N-Methyl-3,5-bis(trifluoromethyl)aniline; 3,5-Bis(trifluoromethyl)-N-methylaniline; N-Methyl-α,α,α,α',α',α'-hexafluoro-3,5-xylidine; 3,5-Di(trifluoromethyl)-N-methylaniline; 3,5-Bis(trifluoromethyl)phenylmethylamine; 1-Methylamino-3,5-bis(trifluoromethyl)benzene; N-Methyl-3,5-di(trifluoromethyl)benzenamine
EINECS	Contact for details

Quality Control

Our N1-Methyl-3,5-Di(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.