Description

3-Amino-2-piperidone-6-carboxylic acid is a high-purity, non-proteinogenic amino acid derivative featuring a unique piperidone ring structure. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its ability to introduce constrained conformational elements into target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Chemistry: Used to construct conformationally restricted peptide analogs, enhancing metabolic stability and receptor selectivity in therapeutic peptides.
• Chemical Biology Probes: Serves as a scaffold for developing enzyme inhibitors, receptor ligands, and other molecular tools for biochemical research.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to generate enantiomerically pure compounds.
• Academic & Industrial R&D: Fundamental building block for methodological development in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: Basis for producing specialized derivatives and fine chemicals tailored to specific client requirements in contract manufacturing.

Basic Information

Product Name	3-Amino-2-Piperidone-6-Carboxylic Acid
CAS No.	42155-74-8
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	3-Amino-2-piperidone-6-carboxylic acid; 3-Amino-2-oxo-6-piperidinecarboxylic acid; 3-Amino-2-piperidinone-6-carboxylic acid; 6-Carboxy-3-amino-2-piperidone; (3S)-3-Amino-2-oxopiperidine-6-carboxylic acid (for specific enantiomer); 3-Amino-delta2-piperidone-6-carboxylic acid; AHPCA; 3-Amino-2-piperidonecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-2-piperidone-6-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications. We support development projects requiring material meeting GMP or other stringent regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (for enantiomeric grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.