Description

D[Leu4,Lys8]-Vp is a synthetic peptide analog, a modified derivative of vasopressin. This compound is significant for its enhanced stability and targeted biological activity compared to its native counterpart, making it a valuable tool in biochemical and pharmacological research. It is primarily needed by research institutions and pharmaceutical developers focusing on neuroendocrinology, metabolic disorders, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard or active agent in studies of vasopressin receptor (V1a, V2) signaling pathways and function.
• Pharmacological Development: Serves as a lead compound or intermediate in the design and synthesis of new peptide-based therapeutics targeting cardiovascular or renal systems.
• In Vitro Assays: Employed in cell-based assays and high-throughput screening (HTS) to evaluate agonist or antagonist activity at relevant receptors.
• Metabolic Studies: Applied in research investigating the role of vasopressin analogs in water homeostasis, blood pressure regulation, and related metabolic processes.
• Academic & Institutional Research: A key reagent for universities and research labs exploring neuropeptide physiology and pathophysiology.

Basic Information

Product Name	D[Leu4,Lys8]-Vp
CAS No.	42061-33-6
Molecular Formula	C46H68N14O12S2
Molecular Weight	1081.26 g/mol
Synonyms	[Deamino-1, D-Leucine-4, Lysine-8]-Vasopressin; dDAVP analog; Desmopressin analog; 1-Deamino-4-D-leucine-8-L-lysine-vasopressin; D-Leu4,Lys8-VP; Vasopressin, 1-(3-mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-4-D-leucine-8-L-lysine-; [Leu4, Lys8]Vp; D(LEU4,LYS8)VP
EINECS	Contact for details

Quality Control

Our D[Leu4,Lys8]-Vp is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.