Description

H-Dl-Tic-Oh CAS NO 41994-51-8 is a non-proteinogenic amino acid derivative, specifically a synthetic analog of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic). This compound serves as a critical chiral building block and a versatile intermediate in advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of peptide drugs and protease inhibitors.
• Biochemical Research: Used as a constrained amino acid analog in peptide structure-activity relationship (SAR) studies.
• Medicinal Chemistry: Serves as a core scaffold for designing and synthesizing novel drug candidates targeting neurological and cardiovascular pathways.
• Peptide Synthesis: Incorporated into custom peptides to confer specific conformational and binding properties.
• Chemical Biology: Employed as a tool compound for probing enzyme active sites and protein-protein interactions.
• Academic Research: Utilized in methodological development for asymmetric synthesis and chiral resolution studies.

Basic Information

Product Name	H-Dl-Tic-Oh
CAS No.	41994-51-8
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	DL-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid; (±)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid; rac-Tic-OH; H-DL-Tic-OH; DL-Tic; Tic-OH; 3-Carboxy-1,2,3,4-tetrahydroisoquinoline; (±)-Tic
EINECS	Contact for details

Quality Control

Our H-Dl-Tic-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Racemic mixture (DL)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.