Description

7-Amino-5-(2-Chlorophenyl)-1,3-Dihydro-3-Hydroxy-2H-1,4-Benzodiazepin-2-One is a high-purity benzodiazepine derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of complex active pharmaceutical ingredients (APIs) and for research into novel therapeutic agents. This compound is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Key intermediate in the synthesis of novel benzodiazepine-based Active Pharmaceutical Ingredients (APIs).
• Building block for research and development of central nervous system (CNS) targeting drugs.
• Precursor in the manufacture of specialized fine chemicals and reference standards.
• Critical material for process development and scale-up in pharmaceutical manufacturing.
• Starting material for academic and industrial research in medicinal chemistry.
• Used in the development of analytical methods and impurity profiling.

Basic Information

Product Name	7-Amino-5-(2-Chlorophenyl)-1,3-Dihydro-3-Hydroxy-2H-1,4-Benzodiazepin-2-One
CAS No.	41993-29-7
Molecular Formula	C15H12ClN3O2
Molecular Weight	301.73 g/mol
Synonyms	7-Amino-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 3-Hydroxy-7-amino-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 2H-1,4-Benzodiazepin-2-one, 7-amino-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-; 7-Amino-5-(o-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Lorazepam Intermediate; 7-Amino Lorazepam Ketone; 41993-29-7
EINECS	Contact for details

Quality Control

Our 7-Amino-5-(2-Chlorophenyl)-1,3-Dihydro-3-Hydroxy-2H-1,4-Benzodiazepin-2-One is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency suitable for pharmaceutical R&D applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.