Description

5-(2-Chlorophenyl)-1,3-Dihydro-3-Hydroxy-7-Nitro-2H-1,4-Benzodiazepin-2-One is a high-purity benzodiazepine derivative, a critical advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex active pharmaceutical ingredients (APIs) and for research into central nervous system (CNS) therapeutics. Pharmaceutical manufacturers and advanced research organizations need this material for developing new drug candidates and for high-value chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and development of new therapeutic agents targeting the central nervous system.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Chemical Synthesis: A versatile intermediate for further chemical modifications and the creation of specialized chemical libraries.
• Preclinical Studies: Utilized in pharmacological and toxicological studies during early-stage drug development.

Basic Information

Item	Details
Product Name	5-(2-Chlorophenyl)-1,3-Dihydro-3-Hydroxy-7-Nitro-2H-1,4-Benzodiazepin-2-One
CAS No.	41993-28-6
Molecular Formula	C15H10ClN3O4
Molecular Weight	331.71 g/mol
Synonyms	7-Nitro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one; 3-Hydroxy-7-nitro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-(2-Chlorophenyl)-3-hydroxy-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Nitro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one; 41993-28-6; 5-(2-Chlorophenyl)-3-hydroxy-7-nitro-1H-1,4-benzodiazepin-2(3H)-one
EINECS	Contact for details

Quality Control

Our 5-(2-Chlorophenyl)-1,3-Dihydro-3-Hydroxy-7-Nitro-2H-1,4-Benzodiazepin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and intermediate use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.