Description

n-Hexadecanoyl-4-Hydroxy-L-Proline is a high-purity, synthetic derivative of the amino acid L-proline, modified with a palmitoyl (hexadecanoyl) chain. This specialized compound is valued for its role as a key intermediate in advanced pharmaceutical synthesis and cosmetic research, offering precise structural control for product development. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, biotechnology, and high-end personal care industries for applications requiring specific lipophilic and chiral properties.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Cosmetic Actives: Used in the formulation of anti-aging and skin-repair serums and creams, leveraging its potential collagen-stimulating properties.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and proteomics research.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to introduce lipophilic character and modify peptide stability.
• Surfactant & Emulsifier Research: Investigated for the development of novel, biocompatible surfactants due to its amphiphilic structure.

Basic Information

Product Name	n-Hexadecanoyl-4-Hydroxy-L-Proline
CAS No.	41736-92-9
Molecular Formula	C21H39NO4
Molecular Weight	369.54 g/mol
Synonyms	Palmitoyl-4-hydroxy-L-proline; 4-Hydroxy-L-proline palmitamide; L-Proline, 4-hydroxy-, N-hexadecanoyl-; N-Palmitoyl-4-hydroxy-L-proline; 1-(1-Oxohexadecyl)-4-hydroxy-L-proline; Hexadecanoylhydroxyproline; N-(1-Oxopalmityl)-4-hydroxy-L-proline; 4-Hydroxyproline palmitic acid amide
EINECS	Contact for details

Quality Control

Our n-Hexadecanoyl-4-Hydroxy-L-Proline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.