Description

6-Fluoro-2,3,4,9-Tetrahydro-1H-Carbazol-1-One is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core carbazole-derived structure, functionalized with a ketone group and a fluorine atom, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by pharmaceutical R&D and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides and fungicides with enhanced efficacy.
• Material Science: Used in the research and development of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Synthesis: A valuable fluorinated building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and molecular diversification.
• Academic & Institutional Research: Employed in universities and research institutes for studying heterocyclic chemistry and fluorine substitution effects.

Basic Information

Product Name	6-Fluoro-2,3,4,9-Tetrahydro-1H-Carbazol-1-One
CAS No.	41734-98-9
Molecular Formula	C₁₂H₁₀FNO
Molecular Weight	203.21 g/mol
Synonyms	6-Fluoro-1,2,3,4-tetrahydrocarbazol-1-one; 6-Fluoro-1-oxo-1,2,3,4-tetrahydrocarbazole; 6-Fluoro-2,3,4,9-tetrahydro-1H-carbazol-1-one; 6-Fluoro-1-keto-1,2,3,4-tetrahydrocarbazole; 6-Fluoro-tetrahydrocarbazolone; 6-F-THCO; 41734-98-9; 6-Fluoro-1,2,3,4-tetrahydro-9H-carbazol-9-one (tautomer)
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2,3,4,9-Tetrahydro-1H-Carbazol-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to cGMP principles ensures reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.