Description

Poly(Lys, Ser) Hydrobromide is a synthetic polypeptide salt composed of lysine and serine residues, widely utilized as a model compound in biochemical research and pharmaceutical development. Its defined structure and cationic nature make it an essential tool for studying peptide-cell interactions, drug delivery mechanisms, and biomaterial surface modifications. This product is critical for researchers and formulators in the fields of biomedical engineering, advanced drug delivery systems, and cosmetic science, where controlled peptide behavior is paramount.

Application

• Biomedical Research: Serves as a model cationic polypeptide for studying cell-penetrating peptides (CPPs), membrane interactions, and intracellular delivery mechanisms.
• Drug Delivery Systems: Used in the development of non-viral gene delivery vectors (polyplexes) and as a component in nanoparticle formulations for encapsulating nucleic acids or drugs.
• Biomaterial Coating: Applied to modify surface properties of implants and scaffolds to enhance cell adhesion, proliferation, and tissue integration.
• Cosmetic Science: Investigated for its potential in topical formulations aimed at skin conditioning and enhancing the penetration of active ingredients.
• Enzyme and Protein Mimetics: Acts as a scaffold for constructing simplified models to understand complex protein folding and function.
• Standard and Reference Material: Provides a well-characterized standard for analytical method development and calibration in peptide analysis laboratories.

Basic Information

Product Name	Poly(Lys, Ser) Hydrobromide
CAS No.	41705-03-7
Molecular Formula	(C9H18N3O3 • C3H7NO3)n • xHBr
Molecular Weight	Variable (Polymer)
Synonyms	Poly(L-lysine, L-serine) hydrobromide; Poly(Lys-Ser) HBr; Lysine-Serine Copolymer Hydrobromide; PLS HBr; Poly(lysine-co-serine) HBr; Cationic Polypeptide Hydrobromide; Poly(L-Lys50, L-Ser50) HBr; Poly(ε-benzyloxycarbonyl-L-lysine-co-O-benzyl-L-serine) hydrobromide (precursor form)
EINECS	Contact for details

Quality Control

Every batch of Poly(Lys, Ser) Hydrobromide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing specific batch results for molecular weight distribution, amino acid composition, purity, and residual solvents is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Amino Acid Ratio (Lys:Ser)	As specified (e.g., 1:1)
Assay (Nitrogen Content)	≥ 95.0%
Molecular Weight (Average)	As per grade (e.g., 1-10 kDa, 10-30 kDa)
Water Content (KF)	≤ 5.0 %
Residual Solvents (GC)	Meets ICH guidelines
Biological Safety (Endotoxin)	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.