Description

(3R)-3,4,5,6-Tetrahydro-4α,5α-Dimethoxy-9-Methyl-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocine-8,10(9H)-Dione is a complex heterocyclic compound featuring a fused pyrimido-oxazocine core structure, which is of significant interest in advanced synthetic chemistry. This compound serves as a high-value synthetic intermediate and building block for the development of novel pharmacologically active molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex nitrogen-containing heterocycles for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in hit-to-lead optimization.
• Organic Synthesis: Serves as a versatile precursor for constructing complex polycyclic frameworks due to its reactive epoxide and lactone functionalities.
• Academic Research: Valuable compound for studying heterocyclic chemistry, reaction mechanisms, and the synthesis of natural product analogs.
• Contract Research Organizations (CROs): Supplied to CROs supporting pharmaceutical and biotechnology companies in their discovery pipelines.
• Fine Chemical Production: Used in the multi-step synthesis of specialized, high-value fine chemicals and advanced materials.

Basic Information

Product Name	(3R)-3,4,5,6-Tetrahydro-4α,5α-Dimethoxy-9-Methyl-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocine-8,10(9H)-Dione
CAS No.	41547-69-7
Molecular Formula	C₁₃H₁₆N₂O₆
Molecular Weight	296.28 g/mol
Synonyms	9-Methyl-3β,6β-epoxy-4α,5α-dimethoxy-3,4,5,6-tetrahydro-2H,8H-pyrimido[6,1-b][1,3]oxazocine-8,10(9H)-dione; (3R)-4α,5α-Dimethoxy-9-methyl-3β,6β-epoxy-3,4,5,6-tetrahydro-2H,8H-pyrimido[6,1-b][1,3]oxazocine-8,10(9H)-dione; Pyrimido[6,1-b][1,3]oxazocine-8,10-dione derivative; CAS 41547-69-7; 41547-69-7.
EINECS	Contact for details

Quality Control

Our (3R)-3,4,5,6-Tetrahydro-4α,5α-Dimethoxy-9-Methyl-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocine-8,10(9H)-Dione is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.