Description

Pht-Lys-Oh CAS NO 41440-64-6 is a specialized protected amino acid derivative, specifically the phthaloyl-protected form of lysine. This compound is a critical building block in modern organic synthesis, particularly for the controlled construction of peptides and complex molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity intermediates for advanced synthesis.

Application

• Peptide Synthesis: Serves as a key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS), enabling the selective incorporation of lysine residues.
• Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) and novel therapeutic peptides.
• Bioconjugation: Acts as a precursor for creating linkers and functionalized molecules used in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Chemical Biology Research: Employed in the synthesis of probes, inhibitors, and other tools for studying biological processes and protein function.
• Fine Chemical Production: Utilized as a chiral building block for the synthesis of complex natural products and specialty chemicals.

Basic Information

Product Name	Pht-Lys-Oh
CAS No.	41440-64-6
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	N6-Phthaloyl-L-lysine; (S)-2-Amino-6-phthalimidohexanoic acid; Phthaloyl-L-lysine; Nε-Phthaloyl-L-lysine; L-Lysine, N6-phthaloyl-; Pht-L-Lys-OH; Fmoc-Lys(Pht)-OH (when used with Fmoc protection); N-Phthalyl-L-lysine
EINECS	Contact for details

Quality Control

Our Pht-Lys-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with your research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Specific range provided on COA
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.