Description

2-(1,1,2,3,3,3-Hexafluoropropoxy)Benzenamine is a specialized fluorinated aromatic amine intermediate of significant interest in advanced chemical synthesis. Its unique structure, featuring a hexafluoropropoxy side chain, provides valuable properties for creating high-performance materials and active pharmaceutical ingredients. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty polymer industries seeking to incorporate fluorine for enhanced stability, lipophilicity, and bioactivity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to modulate metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing dielectric anisotropy and thermal stability.
• Specialty Polymer Modifier: Incorporated into polymer backbones to impart unique surface properties, chemical resistance, and low refractive index for optical applications.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a protected aniline derivative in complex multi-step synthetic routes within R&D laboratories.

Basic Information

Product Name	2-(1,1,2,3,3,3-Hexafluoropropoxy)Benzenamine
CAS No.	41242-02-8
Molecular Formula	C9H7F6NO
Molecular Weight	259.15 g/mol
Synonyms	2-(1,1,2,3,3,3-Hexafluoropropoxy)aniline; 2-(Perfluoroisopropoxy)aniline; 1-Amino-2-(1,1,2,3,3,3-hexafluoropropoxy)benzene; Benzenamine, 2-(1,1,2,3,3,3-hexafluoropropoxy)-; 2-(HFP)Aniline; 2-Amino-1-(1,1,2,3,3,3-hexafluoropropoxy)benzene; 2-(Hexafluoroisopropoxy)phenylamine
EINECS	Contact for details

Quality Control

Our 2-(1,1,2,3,3,3-Hexafluoropropoxy)Benzenamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.