Description

3'-Hydroxy-D-Sepiapterin is a specialized pteridine derivative of significant interest in biochemical research and development. This compound serves as a key intermediate and reference standard in the study of folate metabolism, nitric oxide synthase activity, and related enzymatic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on metabolic disorders and cellular signaling. The high-purity material is essential for ensuring accurate and reproducible experimental results.

Application

• Biochemical Research: Critical intermediate in the study of pterin biosynthesis and folate metabolic cycles.
• Enzyme Substrate/Inhibitor Studies: Used as a substrate or inhibitor in assays for enzymes like nitric oxide synthase (NOS) and phenylalanine hydroxylase.
• Reference Standard: Serves as a high-purity analytical standard for HPLC, LC-MS, or NMR method development and validation in quality control laboratories.
• Pharmaceutical R&D: Investigated in the development of potential therapeutic agents targeting metabolic pathways and neurological conditions.
• Diagnostic Reagent Manufacturing: Employed in the formulation of diagnostic kits and reagents for clinical chemistry.
• Cell Culture & Neuroscience Research: Applied in studies of cell proliferation, differentiation, and neurotransmitter synthesis.

Basic Information

Product Name	3'-Hydroxy-D-Sepiapterin
CAS No.	41230-32-4
Molecular Formula	C9H9N5O4
Molecular Weight	251.20 g/mol
Synonyms	3'-OH-D-Sepiapterin; D-3'-Hydroxysepiapterin; 2-Amino-6-(1,2-dihydroxypropyl)-7,8-dihydro-4(3H)-pteridinone; (R)-2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydropterin-4(3H)-one; Sepiapterin, 3'-hydroxy-, D-; 3'-Hydroxysepiapterin (D-form)
EINECS	Contact for details

Quality Control

Our 3'-Hydroxy-D-Sepiapterin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Custom purity grades and specific impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under appropriate conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥95.0% (Standard Grade), ≥98.0% (High Purity Grade)
Water Content (KF)	≤2.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.