Description

Cyclo(D-Trp-L-Pro-) is a synthetic cyclic dipeptide, also known as a diketopiperazine, derived from the amino acids D-tryptophan and L-proline. This compound is of significant interest in pharmaceutical research and development due to its role as a key structural motif and potential biological activity. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, peptide synthesis, and drug discovery. The product is supplied with the CAS registry number 41222-71-3.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of more complex peptide-based drug candidates and bioactive molecules.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold for studying structure-activity relationships (SAR) and developing new therapeutic agents.
• Biochemical Tool: Employed in biochemical assays to investigate enzyme inhibition, receptor binding, or other biological pathways.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic chemistry, peptide science, and pharmacology.
• Standards & Calibration: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	Cyclo(D-Trp-L-Pro-)
CAS No.	41222-71-3
Molecular Formula	C16H17N3O2
Molecular Weight	283.33 g/mol
Synonyms	Cyclo(D-tryptophyl-L-prolyl); D-Tryptophan-L-proline diketopiperazine; Cyclo(D-Trp-L-Pro) DKP; 3-Benzyl-6-(2-carboxyethyl)-2,5-diketopiperazine (related structure); c(D-Trp-L-Pro); DKPs; Diketopiperazine derivative; Prolyltryptophan anhydride
EINECS	Contact for details

Quality Control

Our Cyclo(D-Trp-L-Pro-) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.