Description

n-(2-Trifluoromethyl-Phenyl)-Guanidine is a specialized guanidine derivative featuring a trifluoromethylphenyl substituent, which imparts unique chemical and physical properties. This compound serves as a valuable high-purity building block and intermediate in advanced organic synthesis, where its structural motifs are critical for developing molecules with targeted functionalities. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides, leveraging the biological activity of the guanidine and trifluoromethyl groups.
• Organic Synthesis Reagent: Acts as a versatile precursor or reagent in nucleophilic substitution and condensation reactions to introduce the guanidine moiety into complex molecules.
• Material Science Research: Potential monomer or additive in the development of specialty polymers and advanced materials with specific thermal or chemical resistance.
• Chemical Biology Probe: Useful in biochemical research as a scaffold for designing enzyme inhibitors or molecular probes due to its hydrogen-bonding capability.

Basic Information

Item	Details
Product Name	n-(2-Trifluoromethyl-Phenyl)-Guanidine
CAS No.	41213-66-5
Molecular Formula	C8H8F3N3
Molecular Weight	203.16 g/mol
Synonyms	1-(2-(Trifluoromethyl)phenyl)guanidine; N-(2-Trifluoromethylphenyl)guanidine; 2-(Trifluoromethyl)phenylguanidine; Guanidine, N-[2-(trifluoromethyl)phenyl]-; 2-Trifluoromethylphenylguanidine; (2-Trifluoromethylphenyl)guanidine; 1-(2-Trifluoromethylphenyl)guanidine; 2-(Trifluoromethyl)anilinocarboximidamide
EINECS	Contact for details

Quality Control

Our n-(2-Trifluoromethyl-Phenyl)-Guanidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.