Description

Apramycin Sulfate is a water-soluble aminoglycoside antibiotic derived from *Streptomyces tenebrarius*. This compound is valued for its broad-spectrum activity against Gram-negative bacteria and specific efficacy against strains resistant to other aminoglycosides. It is a critical raw material for manufacturers in the veterinary pharmaceutical and animal health industries, primarily used in the formulation of treatments for gastrointestinal infections in livestock and poultry.

Application

• Veterinary Pharmaceutical Formulations: Primary active ingredient in injectable solutions, oral powders, and premixes for the treatment of bacterial enteritis in swine, cattle, and poultry.
• Animal Feed Additives: Incorporated into medicated feed to promote growth and prevent bacterial infections in commercial farming operations.
• Aquaculture: Used for the control of bacterial diseases in farmed fish and shrimp.
• Research & Development: Serves as a reference standard and active pharmaceutical ingredient (API) in microbiological and pharmacological research.
• API Manufacturing: Sourced as a high-purity active pharmaceutical ingredient for GMP-compliant production of finished veterinary dosage forms.

Basic Information

Product Name	Apramycin Sulfate
CAS No.	41194-16-5
Molecular Formula	C21H41N5O11 • xH2SO4
Molecular Weight	539.6 g/mol (for free base)
Synonyms	Apramycin Sulphate; Nebramycin II; Antibiotic 44768; APR; Apramycin Sulfate Salt; 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-(3-deoxy-4-C-methyl-3-methylamino-β-L-arabinopyranosyl)-2-deoxy-D-streptamine Sulfate
EINECS	Contact for details

Quality Control

Our Apramycin Sulfate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as potency, purity, and residual solvents. We can support compliance with relevant veterinary pharmacopoeia standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0% (on dried basis)
pH (10% solution)	5.0 - 7.0
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.