Description

2-Fluorocinnamalmalononitrile is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. Its core value lies in its unique molecular structure, which combines a fluorinated aromatic system with a reactive malononitrile moiety, making it a versatile precursor for constructing complex heterocycles and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated scaffolds into target molecules to modulate their biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom can enhance bioactivity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Biology Probes: Utilized in the creation of fluorinated probes and tags for studying biological mechanisms and enzyme interactions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including cyclization and cross-coupling reactions.

Basic Information

Product Name	2-Fluorocinnamalmalononitrile
CAS No.	41122-44-5
Molecular Formula	C₁₂H₇FN₂
Molecular Weight	198.20 g/mol
Synonyms	2-Fluorocinnamylidenemalononitrile; (2-Fluorobenzylidene)malononitrile; 2-Fluoro-α-(cyanomethylidene)benzenepropanenitrile; (E)-2-(2-Fluorobenzylidene)malononitrile; α-((2-Fluorophenyl)methylene)malononitrile; Propanenitrile, 2-fluoro-3-phenyl-2-propenylidene-; 2-Fluorocinnalmalononitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Fluorocinnamalmalononitrile is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.