Description

Dihydrosomatostatin is a synthetic peptide analog of the endogenous hormone somatostatin, characterized by its reduced form. This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its potential for enhanced stability and modified biological activity. It serves as a critical intermediate and reference standard for researchers and manufacturers in the fields of endocrinology, oncology, and metabolic disorder therapeutics.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of novel somatostatin analogs and peptide-based therapeutics.
• Biochemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in peptide analysis.
• Endocrinology Studies: Employed in in-vitro and in-vivo research to investigate growth hormone regulation, insulin secretion, and neurotransmitter functions.
• Oncology Research: Utilized in studies targeting somatostatin receptors (SSTRs) overexpressed in various neuroendocrine and other tumors.
• Metabolic Disorder Research: Applied in preclinical research for conditions like acromegaly, gigantism, and severe diarrhea associated with certain cancers.
• Peptide Chemistry: Acts as a building block or model compound for studying peptide stability, reduction reactions, and structure-activity relationships (SAR).

Basic Information

Product Name	Dihydrosomatostatin
CAS No.	40958-31-4
Molecular Formula	C76H104N18O19S2
Molecular Weight	1637.9 g/mol
Synonyms	Dihydro-Somatostatin; [Dihydro]Somatostatin; Somatostatin, dihydro-; Alamandine; H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (cyclic 3-14 disulfide, reduced); Reduced Somatostatin; SRIF (1-14), reduced; Growth Hormone Release-Inhibiting Hormone, dihydro-
EINECS	Contact for details

Quality Control

Our Dihydrosomatostatin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, ensuring it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the product should be handled under anhydrous conditions and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Maximum Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.