Description

[Asu1,6,Arg8]-Vasopressin is a synthetic analogue of the neurohypophysial hormone vasopressin, specifically engineered for enhanced stability and targeted biological activity. This modified peptide is of significant interest in advanced biomedical research and pharmaceutical development due to its potential for studying vasopressor and antidiuretic receptor pathways. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers engaged in endocrinology, cardiovascular research, and novel therapeutic agent discovery.

Application

• Biomedical Research: Fundamental studies on vasopressin receptor (V1a, V2) signaling, function, and modulation.
• Drug Discovery & Development: Serving as a key reference standard or lead compound in the development of novel therapeutics for conditions like diabetes insipidus, septic shock, or cardiovascular disorders.
• Pharmacological Assays: Use in in vitro and in vivo assays to evaluate pressor activity, antidiuretic effects, and metabolic responses.
• Biochemical Standard: Acting as a high-purity calibrant or control in analytical methods such as HPLC and mass spectrometry for peptide quantification.
• Academic Research: Investigating the structure-activity relationships (SAR) of peptide hormones and the impact of specific amino acid substitutions.

Basic Information

Product Name	[Asu1,6,Arg8]-Vasopressin
CAS No.	40944-53-4
Molecular Formula	C46H65N15O12S2
Molecular Weight	1052.2 g/mol
Synonyms	1-(3-Mercaptopropanoic acid)-6-L-asparagine-8-L-arginine-vasopressin; [1-Deamino, 6-L-Asn, 8-L-Arg]-Vasopressin; dAVP; Desmopressin analogue; Argipressin, 1-deamino-6-L-asparagine-8-L-arginine-; 1-Desamino-6-L-asparagine-8-L-arginine vasopressin
EINECS	Contact for details

Quality Control

Our [Asu1,6,Arg8]-Vasopressin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis to meet specific purity or packaging requirements is available.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.