Description

Z-Leu-Tyr-OH is a protected dipeptide building block, specifically a Z-protected leucine-tyrosine derivative. This compound is essential for solid-phase peptide synthesis (SPPS), providing a crucial intermediate for constructing larger, biologically active peptide sequences. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide drug discovery, development, and production.

Application

• Peptide Synthesis Intermediate: A key building block in the solid-phase and solution-phase synthesis of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of novel therapeutic peptides targeting various diseases.
• Biochemical Research: Serves as a substrate or standard in enzymatic studies and proteomics research.
• API Development: Employed in the process development and scale-up of peptide-based Active Pharmaceutical Ingredients (APIs).
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening of bioactive compounds.

Basic Information

Product Name	Z-Leu-Tyr-OH
CAS No.	40908-35-8
Molecular Formula	C23H28N2O6
Molecular Weight	428.48 g/mol
Synonyms	N-Carbobenzoxy-L-leucyl-L-tyrosine; Z-L-Leucyl-L-tyrosine; CBZ-Leu-Tyr-OH; Nα-(Benzyloxycarbonyl)-L-leucyl-L-tyrosine; Benzyl N-[(2S)-1-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methyl-1-oxopentan-2-yl]carbamate; N-Benzyloxycarbonylleucyltyrosine; Z-Leu-Tyr; Z-Leu-Tyrosine
EINECS	Contact for details

Quality Control

Our Z-Leu-Tyr-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	-15° to -20° (c=1 in DMF)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.