Description

H-Met-Thr-Oh CAS NO 40883-16-7 is a high-purity, protected amino acid derivative, specifically the hydrochloride salt of N-Formyl-L-methionyl-L-threonine. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptide sequences. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptide hormones, and biochemical research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential construction of custom peptide chains.
• Pharmaceutical R&D: Used in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies of protein structure-function relationships and enzyme substrates.
• Production of Biologically Active Peptides: A precursor for synthesizing peptides with potential hormonal, antimicrobial, or signaling activities.
• Combinatorial Chemistry Libraries: Serves as a building block for creating diverse peptide libraries for drug discovery screening.

Basic Information

Product Name	H-Met-Thr-Oh
CAS No.	40883-16-7
Molecular Formula	C10H19N2O5S • HCl
Molecular Weight	324.80 g/mol
Synonyms	N-Formyl-L-methionyl-L-threonine hydrochloride; F-Met-Thr-OH • HCl; N-Formylmethionylthreonine hydrochloride; L-Threonine, N-formyl-L-methionyl-, hydrochloride; Formylmethionylthreonine HCl; Protected Methionine-Threonine dipeptide; FMOC SPPS building block (related); Peptide synthesis intermediate
EINECS	Contact for details

Quality Control

Our H-Met-Thr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.