Description

(2R,5S)-2,5-Diaminoadipic Acid is a high-purity, stereochemically defined chiral diaminodicarboxylic acid, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex molecules, particularly in pharmaceutical research and peptide chemistry, where precise stereochemistry is paramount for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications in drug discovery, asymmetric synthesis, and the development of novel peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Peptide Synthesis: Used as a constrained, non-proteinogenic amino acid derivative to introduce specific structural motifs and enhance the metabolic stability of therapeutic peptides.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for the development of chiral ligands and organocatalysts used in enantioselective transformations.
• Biochemical Research: Employed in studies of enzyme mechanisms and metabolic pathways involving lysine and glutaric acid metabolism.
• Material Science: Potential monomer for the synthesis of novel polyamides and other specialty polymers with unique thermal and mechanical properties.

Basic Information

Product Name	(2R,5S)-2,5-Diaminoadipic Acid
CAS No.	40872-10-4
Molecular Formula	C6H12N2O4
Molecular Weight	176.17 g/mol
Synonyms	(2R,5S)-2,5-Diaminohexanedioic Acid; (2R,5S)-Diaminoadipic Acid; (2R,5S)-DAAA; (2R,5S)-Hexanedioic acid, 2,5-diamino-; L-2,5-Diaminoadipic Acid (stereospecific); (2R,5S)-2,5-Diaminosuberic Acid precursor; (2R,5S)-Diaminopimelic Acid isomer
EINECS	Contact for details

Quality Control

Our (2R,5S)-2,5-Diaminoadipic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess, and specific impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.