Description

6-(4-Hydroxyphenylhydrazino)Uracil is a specialized heterocyclic organic compound that serves as a key synthetic intermediate in advanced pharmaceutical and biochemical research. Its unique molecular structure, featuring both uracil and hydrazine functionalities, makes it a valuable precursor for developing novel nucleoside analogs and enzyme inhibitors. This high-purity compound is primarily utilized by research institutions and pharmaceutical developers focused on oncology, virology, and metabolic disorder therapeutics.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel nucleoside-based drug candidates and prodrugs.
• Biochemical Research: Used in studies targeting thymidylate synthase and other pyrimidine metabolism enzymes for potential cancer therapies.
• Antiviral Agent Development: Serves as a precursor for compounds being investigated for their activity against viral replication.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic systems in medicinal chemistry.
• Analytical Reference Standard: Employed as a high-purity standard in HPLC and LC-MS methods for quality control in API manufacturing.

Basic Information

Product Name	6-(4-Hydroxyphenylhydrazino)Uracil
CAS No.	40855-14-9
Molecular Formula	C10H10N4O3
Molecular Weight	234.21 g/mol
Synonyms	6-[(4-Hydroxyphenyl)hydrazinyl]-1,2,3,4-tetrahydro-2,4-pyrimidinedione; 6-(p-Hydroxyphenylhydrazino)uracil; 4-Hydroxybenzenehydrazine uracil derivative; Uracil, 6-(4-hydroxyphenylhydrazino)-; 2,4(1H,3H)-Pyrimidinedione, 6-[(4-hydroxyphenyl)hydrazinyl]-
EINECS	Contact for details

Quality Control

Our 6-(4-Hydroxyphenylhydrazino)Uracil is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and specifications can be aligned with client requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere when appropriate for long-term stability. Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.