Description

2-Oxo-1,2-Dihydro-Pyrimidine-5-Sulfonic Acid is a versatile and reactive heterocyclic sulfonic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, combining a pyrimidinone core with a sulfonic acid group, enabling its use in the creation of complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the pyrimidine scaffold is active.
• Dye & Pigment Manufacturing: Acts as a precursor for sulfonated heterocyclic dyes, enhancing water solubility and color fastness.
• Ligand & Catalyst Development: The sulfonic acid and carbonyl groups make it a useful building block for creating chelating ligands and organocatalysts.
• Polymer Modification: Can be incorporated into polymer chains to introduce sulfonic acid functionality for ion-exchange resins or proton-conducting membranes.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Oxo-1,2-Dihydro-Pyrimidine-5-Sulfonic Acid
CAS No.	40828-51-1
Molecular Formula	C4H4N2O4S
Molecular Weight	176.15 g/mol
Synonyms	5-Sulfouracil; 2,4-Dihydroxypyrimidine-5-sulfonic acid; Uracil-5-sulfonic acid; 5-Sulfonic acid uracil; 2,4(1H,3H)-Pyrimidinedione, 5-sulfo-; 5-Sulfopyrimidine-2,4(1H,3H)-dione; 5-Sulfonato-2,4-dihydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 2-Oxo-1,2-Dihydro-Pyrimidine-5-Sulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.