Description

5-(Trifluoromethyl)-1H-[1,2,4]Triazolo[1,5-A]Pyrimidin-7-One is a high-value, fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring a fused triazolopyrimidine core with a trifluoromethyl group, makes it an essential intermediate for developing novel active ingredients. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the discovery and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Investigated as a precursor for specialty chemicals, including ligands for catalysis or components for advanced polymeric materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity fluorinated heterocycles.

Basic Information

Product Name	5-(Trifluoromethyl)-1H-[1,2,4]Triazolo[1,5-A]Pyrimidin-7-One
CAS No.	40775-91-5
Molecular Formula	C6H2F3N5O
Molecular Weight	217.11 g/mol
Synonyms	5-(Trifluoromethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one; 5-(Trifluoromethyl)-7-hydroxy-[1,2,4]triazolo[1,5-a]pyrimidine; 5-Trifluoromethyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one; 40775-91-5; 5-(Trifluoromethyl)-1,2,4-triazolo[1,5-a]pyrimidin-7-ol; 5-Trifluoromethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
EINECS	Contact for details

Quality Control

Our production of 5-(Trifluoromethyl)-1H-[1,2,4]Triazolo[1,5-A]Pyrimidin-7-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.