Description

D-Oxazepam CAS NO 40762-00-3 is a deuterated analog of the benzodiazepine derivative oxazepam, where specific hydrogen atoms are replaced with the stable isotope deuterium. This modification is strategically important for enhancing metabolic stability and is a critical tool in pharmaceutical research and development. It is primarily utilized by research chemists, analytical laboratories, and pharmaceutical companies engaged in drug metabolism and pharmacokinetics (DMPK) studies, analytical method development, and the synthesis of internal standards.

Application

• As a stable isotope-labeled internal standard for the precise quantification of oxazepam in biological matrices using LC-MS/MS and GC-MS.
• In drug metabolism studies (DMPK) to investigate metabolic pathways, bioavailability, and half-life through isotope tracing.
• For the development and validation of analytical methods in forensic, clinical, and pharmaceutical quality control laboratories.
• In pharmaceutical research for synthesizing novel deuterated drug candidates aimed at improving pharmacokinetic profiles.
• As a reference material in certified standards for calibration and ensuring analytical accuracy.

Basic Information

Product Name	D-Oxazepam
CAS No.	40762-00-3
Molecular Formula	C15H10DClN2O2
Molecular Weight	~287.72 g/mol
Synonyms	Deuterated Oxazepam; Oxazepam-d5 (common designation); 7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one deuterated; [2H5]-Oxazepam; 3-Hydroxydiazepam-d5; Serax-d5 (deuterated analog); Lorazepam related compound D (deuterated); Benzodiazepine-d5 internal standard.
EINECS	Contact for details

Quality Control

Our D-Oxazepam is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for chemical purity and isotopic enrichment, and is accompanied by a detailed Certificate of Analysis (COA). We ensure compliance with relevant standards for high-purity reference materials, supporting reliable and reproducible research outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.