Description

5-Fluorobenzo[B]Thiophene-3-Carbaldehyde is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional reactivity, featuring both an electron-deficient thiophene ring and a formyl group, making it a critical precursor for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Serves as a monomer or building block for the synthesis of organic semiconductors, conductive polymers, and liquid crystals.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions in fluorinated heterocycle chemistry and as a ligand precursor in catalysis.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating specialized fluorophores and colorants with unique photophysical properties.

Basic Information

Product Name	5-Fluorobenzo[B]Thiophene-3-Carbaldehyde
CAS No.	40740-56-5
Molecular Formula	C9H5FOS
Molecular Weight	180.20 g/mol
Synonyms	5-Fluorobenzo[b]thiophene-3-carboxaldehyde; 5-Fluoro-1-benzothiophene-3-carbaldehyde; 5-Fluoro-benzo[b]thiophene-3-carbaldehyde; 3-Formyl-5-fluorobenzo[b]thiophene; 5-Fluorobenzo[b]thien-3-ylcarboxaldehyde; 5-Fluoro-3-thianaphthenecarboxaldehyde; 5-Fluoro-1-benzothiophene-3-carboxaldehyde; 5-F-BT-3-CHO
EINECS	Contact for details

Quality Control

Our 5-Fluorobenzo[B]Thiophene-3-Carbaldehyde is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.