Description

5-Amidinooxy-L-Norvaline is a specialized amino acid derivative featuring an amidinooxy functional group. This compound is of significant interest in biochemical research and pharmaceutical development due to its potential as a nitric oxide synthase (NOS) inhibitor. It is primarily utilized by research institutions and pharmaceutical companies engaged in the study of cardiovascular, neurological, and inflammatory pathways where nitric oxide signaling plays a critical role.

Application

• Biochemical Research: Used as a selective inhibitor in enzymatic studies to investigate the function and regulation of nitric oxide synthase isoforms.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the discovery and development of novel therapeutics targeting conditions like hypertension, septic shock, and neurodegenerative diseases.
• Academic Studies: Employed in university and institutional labs for fundamental research on cell signaling, vascular biology, and immune response mechanisms.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in analytical chemistry laboratories.
• Peptide Synthesis: Can be incorporated into synthetic peptides to study structure-activity relationships or to create novel bioactive compounds.

Basic Information

Product Name	5-Amidinooxy-L-Norvaline
CAS No.	40736-35-4
Molecular Formula	C6H13N3O3
Molecular Weight	175.19 g/mol
Synonyms	L-N5-(Aminoiminomethyl)ornithine; 5-(Aminoiminomethyl)amino-L-norvaline; L-N5-(Amidino)ornithine; 5-Amidinoaminonorvaline; (S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid; N5-Amidino-L-ornithine; L-NIL (Note: L-NIL typically refers to N6-(1-Iminoethyl)-L-lysine, a related compound; this is a distinct molecule)
EINECS	Contact for details

Quality Control

Our 5-Amidinooxy-L-Norvaline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: Specific range available on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.