Description

Benzenemethanol, α-(Fluoromethyl)-4-Nitro- (9Ci) is a specialized fluorinated nitrobenzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluoromethyl and a nitro group on the benzyl alcohol core, makes it a valuable precursor for developing novel pharmaceuticals and agrochemicals. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and stability.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes and tags used in biochemical and cellular studies.
• Material Science Precursor: Potential monomer or modifier in the synthesis of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed and other metal-mediated coupling reactions to construct complex biaryl and other aromatic systems.
• Fluorine Chemistry Library Synthesis: An important component in combinatorial chemistry for generating diverse fluorinated compound libraries for high-throughput screening.

Basic Information

Product Name	Benzenemethanol, α-(Fluoromethyl)-4-Nitro- (9Ci)
CAS No.	40733-89-9
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	α-(Fluoromethyl)-4-nitrobenzenemethanol; 4-Nitro-α-(fluoromethyl)benzyl alcohol; (4-Nitrophenyl)(fluoromethyl)methanol; 1-(Fluoromethyl)-1-(4-nitrophenyl)methanol; 4-Nitrobenzylfluoromethanol; 4-Nitro-α-fluoromethylbenzyl alcohol; (4-Nitrophenyl)(fluoromethyl)carbinol; 1-(4-Nitrophenyl)-1-fluoromethanol
EINECS	Contact for details

Quality Control

Our Benzenemethanol, α-(Fluoromethyl)-4-Nitro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for the production of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.