Description

2-Amino-3-Hydroxy-4-Methylpentanedioic Acid is a specialized chiral amino acid derivative with significant relevance in advanced organic synthesis and pharmaceutical research. Its unique structure, featuring multiple functional groups, makes it a valuable building block for creating complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications in drug discovery, peptide synthesis, and as a precursor for bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for neurological and metabolic drugs.
• Peptide Synthesis: Used as a non-proteinogenic amino acid building block to introduce specific structural and functional motifs into synthetic peptides.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Agrochemical Development: Employed in the synthesis of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Acts as a precursor for specialty chemicals, including chiral ligands for asymmetric catalysis and advanced materials.
• Nutritional Science Research: Investigated for its potential role in specialized nutritional formulations and metabolic studies.

Basic Information

Product Name	2-Amino-3-Hydroxy-4-Methylpentanedioic Acid
CAS No.	40580-64-1
Molecular Formula	C6H11NO5
Molecular Weight	177.16 g/mol
Synonyms	4-Methyl-2-amino-3-hydroxypentanedioic acid; 3-Hydroxy-4-methyl-2-aminopentanedioic acid; (2S,3S,4S)-2-Amino-3-hydroxy-4-methylpentanedioic acid; allo-Threonine derivative; A branched-chain hydroxy amino acid; 2-Amino-3-hydroxy-4-methylglutaric acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Hydroxy-4-Methylpentanedioic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.