Description

2-Chloro-5-Fluoro-4-Piperidin-1-Yl-Pyrimidine is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological or material properties. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced crop protection agents and herbicides.
• Chemical Research: Serves as a versatile building block for constructing complex heterocyclic libraries in medicinal and combinatorial chemistry.
• Material Science: Potential precursor for the synthesis of organic electronic materials and liquid crystals.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Chloro-5-Fluoro-4-Piperidin-1-Yl-Pyrimidine
CAS No.	40423-82-3
Molecular Formula	C9H12ClFN3
Molecular Weight	215.66 g/mol
Synonyms	4-(1-Piperidinyl)-2-chloro-5-fluoropyrimidine; 2-Chloro-5-fluoro-4-(1-piperidinyl)pyrimidine; 2-Chloro-5-fluoro-4-piperidin-1-ylpyrimidine; 2-Chloro-5-fluoro-4-(piperidin-1-yl)pyrimidine; 40423-82-3; 4-Piperidin-1-yl-2-chloro-5-fluoropyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-4-Piperidin-1-Yl-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.