Description

(Prolyl-Hydroxylprolyl-Glycine)10 CAS NO 40350-90-1 is a synthetic, high-purity oligopeptide sequence composed of ten repeating units of the Pro-Hyp-Gly tripeptide motif. This compound is of significant interest as a model collagen-like peptide for advanced biochemical and materials science research. It serves as a critical reference standard and building block for scientists and manufacturers in the fields of biomaterials, cosmetic science, and pharmaceutical development, enabling the study of collagen stability, self-assembly, and bioactivity.

Application

• Biomedical Research: As a well-defined model for studying collagen triple-helix formation, stability, and interactions.
• Cosmetic & Skincare Actives: Used in the development and testing of anti-aging and skin-repair formulations that aim to support collagen structure.
• Biomaterial Engineering: Serves as a fundamental component or cross-linking agent in the design of synthetic extracellular matrices and hydrogels.
• Pharmaceutical Development: Employed as a reference standard in analytical method development and quality control for collagen-related therapeutics.
• Nutraceuticals: Investigated for potential use in bioactive supplements targeting connective tissue health.
• Academic & Industrial R&D: A key reagent for fundamental studies in peptide chemistry, molecular self-assembly, and protein folding.

Basic Information

Product Name	(Prolyl-Hydroxylprolyl-Glycine)10
CAS No.	40350-90-1
Molecular Formula	C90H135N30O33
Molecular Weight	~2096.2 g/mol
Synonyms	(Pro-Hyp-Gly)10; Poly(Pro-Hyp-Gly); Collagen Model Peptide (Pro-Hyp-Gly)10; (L-Prolyl-4-hydroxy-L-prolyl-glycyl)10; POG10; (Pro-Hyp-Gly) decamer; H-(Pro-Hyp-Gly)10-OH; Synthetic collagen-like peptide
EINECS	Contact for details

Quality Control

Our (Prolyl-Hydroxylprolyl-Glycine)10 is produced under stringent conditions to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and NMR. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.