Description

H-Gly-Leu-Met-NH2 HCl is a high-purity tripeptide derivative, specifically the hydrochloride salt of the C-terminal amide. This compound, identified by CAS No. 40297-96-9, is a valuable building block in advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications requiring specific peptide sequences with modified termini.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor or a model compound in the research and development of novel peptide-based therapeutics.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, receptor-ligand binding assays, and metabolic pathway investigations.
• Proteomics & Peptide Synthesis: An essential building block in solid-phase and solution-phase peptide synthesis (SPPS) for constructing custom peptide sequences.
• Cosmeceutical Development: Investigated for potential use in advanced skincare formulations targeting specific biological pathways.
• Academic Research: Employed in university and institutional labs for studying peptide structure, stability, and function.

Basic Information

Product Name	H-Gly-Leu-Met-NH2 HCl
CAS No.	40297-96-9
Molecular Formula	C14H28N4O4S • HCl
Molecular Weight	393.92 g/mol (Free base: 356.46 g/mol)
Synonyms	Glycyl-leucyl-methioninamide hydrochloride; H-Gly-Leu-Met-NH2 • HCl; GLY-LEU-MET-NH2 HYDROCHLORIDE; 40297-96-9; Tripeptide amide derivative; Boc-Gly-Leu-Met-NH2 (precursor); G-L-M-NH2 HCl; Peptide Sequence 46-48 Amide
EINECS	Contact for details

Quality Control

Every batch of H-Gly-Leu-Met-NH2 HCl is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with high-grade standards for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Titration)	97.0% - 102.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.