Description

H-Leu-Ser-Phe-Oh is a synthetic tripeptide composed of the amino acids L-Leucine, L-Serine, and L-Phenylalanine. This compound serves as a crucial building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutic agents and conducting biochemical studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or substrate in enzymatic studies, receptor-ligand binding assays, and metabolic pathway research.
• Peptide Library Construction: An essential component in solid-phase and solution-phase peptide synthesis for creating diverse peptide libraries for screening.
• Cosmetic Peptide Development: Investigated for potential use in the formulation of advanced cosmeceuticals and anti-aging skincare products.
• Academic & Industrial R&D: Serves as a model compound for studying peptide stability, folding, and structure-activity relationships (SAR).

Basic Information

Product Name	H-Leu-Ser-Phe-Oh
CAS No.	40290-77-5
Molecular Formula	C20H31N3O5
Molecular Weight	393.48 g/mol
Synonyms	L-Leucyl-L-seryl-L-phenylalanine; Leu-Ser-Phe; H-Leu-Ser-Phe-OH; L-Leu-L-Ser-L-Phe-OH; NSC 334906; Tripeptide (Leu-Ser-Phe); N-(N-L-Leucyl-L-seryl)-L-phenylalanine; 2-[[2-[[2-[(2-Amino-4-methylpentanoyl)amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]acetic acid
EINECS	Contact for details

Quality Control

Our H-Leu-Ser-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, chiral integrity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (all L-isomers)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.