Description

1-C-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-1-S-Isobutyl-1-Thio-D-Xylitol 3,4-Diacetate is a specialized nucleoside analogue derivative, a key intermediate in advanced pharmaceutical synthesis. This compound matters for its role in the development of novel antiviral and anticancer agents, offering researchers a precise building block for modifying nucleoside structures. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on nucleoside-based drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of modified nucleoside analogues for antiviral and anticancer drug candidates.
• Antiviral Research: Used in the development of nucleotide-based therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating novel chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Tool: Employed in enzymatic studies and as a substrate analog to investigate nucleoside-metabolizing enzymes.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for complex nucleoside derivatives under GMP conditions.
• Academic Research: A valuable compound for universities and research institutes studying nucleic acid chemistry and medicinal chemistry.

Basic Information

Product Name	1-C-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-1-S-Isobutyl-1-Thio-D-Xylitol 3,4-Diacetate
CAS No.	40031-70-7
Molecular Formula	C18H25N5O5S
Molecular Weight	407.48 g/mol
Synonyms	9-(2,5-Anhydro-1-S-isobutyl-3,4-di-O-acetyl-1-thio-D-xylitol-1-yl)adenine; 1-C-(6-Aminopurin-9-yl)-2,5-anhydro-1-S-isobutyl-1-thio-D-xylitol 3,4-diacetate; 2,5-Anhydro-1-S-isobutyl-1-thio-D-xylitol-1-yladenine 3,4-diacetate; Isobutylthio-D-xylitol Adenine Derivative; Nucleoside Thioether Intermediate; Adenine Xylitol Thioacetate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-C-(6-Amino-9H-Purin-9-Yl)-2,5-Anhydro-1-S-Isobutyl-1-Thio-D-Xylitol 3,4-Diacetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.