Description

Amino Acid Hydroxamates L-Tyrosine Hydroxamate is a specialized hydroxamic acid derivative of the essential amino acid L-Tyrosine. This compound is valued for its potent metal-chelating properties, which are central to its function in research and industrial applications. It serves as a critical biochemical tool and intermediate for scientists and manufacturers in the pharmaceutical, biotechnology, and chemical synthesis sectors, particularly in the development of enzyme inhibitors and metalloprotease research.

Application

• Biochemical Research: Used as a potent and selective inhibitor for metalloenzymes, including matrix metalloproteinases (MMPs) and angiotensin-converting enzyme (ACE), in mechanistic and pharmacological studies.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel drug candidates targeting conditions like hypertension, cancer, and inflammatory diseases.
• Chelation Therapy Studies: Investigated for its ability to bind and sequester specific metal ions (e.g., iron, zinc) in models of metal overload and related disorders.
• Proteomics & Diagnostics: Employed in the design of affinity probes and activity-based probes for detecting and characterizing metalloprotease activity in complex biological samples.
• Chemical Synthesis: Acts as a versatile chiral synthon for constructing more complex molecules with hydroxamate functionality for material science and catalysis.
• Agricultural Chemistry: Explored for the development of novel fungicides or herbicides that target metal-dependent processes in plant pathogens.

Basic Information

Product Name	Amino Acid Hydroxamates L-Tyrosine Hydroxamate
CAS No.	4985-42-6
Molecular Formula	C9H12N2O4
Molecular Weight	212.20 g/mol
Synonyms	L-Tyrosine Hydroxamic Acid; (2S)-2-Amino-3-(4-hydroxyphenyl)propanehydroxamic acid; Tyrosinehydroxamic acid; H-Tyr-NHOH; N-Hydroxy-L-tyrosinamide; 4-Hydroxy-L-phenylalanine hydroxamate; L-Tyrosine, N-hydroxy-; (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid hydroxamate
EINECS	Contact for details

Quality Control

Our L-Tyrosine Hydroxamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is easily oxidized; for long-term storage, consider under an inert atmosphere such as argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.