Description

2-Chloro-5-Hydroxypyrimidine is a versatile heterocyclic building block and key pharmaceutical intermediate. This compound is essential for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing pyrimidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside analogs, antiviral drugs, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Serves as a starting material for creating complex ligands, dyes, and specialty chemicals.
• Research & Development: Employed in academic and industrial R&D for medicinal chemistry and material science projects.
• API Manufacturing: Integrated into the production chain for various Active Pharmaceutical Ingredients requiring a functionalized pyrimidine core.

Basic Information

Product Name	2-Chloro-5-Hydroxypyrimidine
CAS No.	4983-28-2
Molecular Formula	C4H3ClN2O
Molecular Weight	130.53 g/mol
Synonyms	5-Hydroxy-2-chloropyrimidine; 2-Chloro-5-pyrimidinol; 2-Chloropyrimidin-5-ol; 5-Chloro-2-hydroxypyrimidine (tautomer); 2-Chloro-5-hydroxypyrimidine; 2-Chloro-5(1H)-pyrimidinone; 5-Hydroxy-2-chloro-1,3-diazine
EINECS	225-635-9

Quality Control

Our 2-Chloro-5-Hydroxypyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.