Description

5-(Benzyloxy)-4-Chloro-2-(Methylthio)-Pyrimidine is a versatile pyrimidine derivative, a crucial building block in advanced organic synthesis. Its molecular structure, featuring protected hydroxyl and reactive chloro and methylthio groups, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of nucleoside analogs, antiviral agents, and other biologically active pyrimidine-based compounds.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Used in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for constructing complex heterocyclic libraries in medicinal chemistry.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to laboratories for custom synthesis and process development projects.

Basic Information

Product Name	5-(Benzyloxy)-4-Chloro-2-(Methylthio)-Pyrimidine
CAS No.	4973-78-8
Molecular Formula	C12H11ClN2OS
Molecular Weight	266.75 g/mol
Synonyms	4-Chloro-2-(methylthio)-5-(phenylmethoxy)pyrimidine; 2-(Methylthio)-4-chloro-5-benzyloxypyrimidine; 5-Benzyloxy-4-chloro-2-methylthiopyrimidine; 4-Chloro-5-(benzyloxy)-2-(methylsulfanyl)pyrimidine; 2-Methylsulfanyl-4-chloro-5-benzyloxypyrimidine; 4973-78-8; Pyrimidine, 5-(benzyloxy)-4-chloro-2-(methylthio)-
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxy)-4-Chloro-2-(Methylthio)-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.