Description

trans-Cinnamoyl-Phe-Oh is a high-purity, synthetic dipeptide derivative featuring a cinnamoyl protecting group. This compound serves as a critical building block and intermediate in advanced organic synthesis, particularly for peptide-based research and development. It is essential for pharmaceutical researchers, fine chemical manufacturers, and academic institutions engaged in the development of novel bioactive compounds and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry: Building block for creating compound libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Cosmetic Peptides: Potential intermediate in the development of anti-aging or skin-conditioning peptide actives.
• Academic & Institutional R&D: Used in university and research institute laboratories for teaching and investigating peptide chemistry.

Basic Information

Product Name	trans-Cinnamoyl-Phe-Oh
CAS No.	4950-65-6
Molecular Formula	C₁₈H₁₇NO₄
Molecular Weight	311.33 g/mol
Synonyms	N-[(E)-Cinnamoyl]-L-phenylalanine; (2S)-2-[[(2E)-3-Phenylprop-2-enoyl]amino]-3-phenylpropanoic acid; Cinnamoyl-L-phenylalanine; trans-Cinnamoyl-L-phenylalanine; Cinn-Phe-OH; N-Cinnamoylphenylalanine; L-Phenylalanine, N-[(E)-3-phenyl-2-propenoyl]-; Fmoc-Phe(4-Cinnamoyl)-OH (related protected form)
EINECS	Contact for details

Quality Control

Our trans-Cinnamoyl-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.