Description

Proline, 5-Oxo-1-Vinyl-, L- (7Ci,8Ci) CAS NO 4931-75-3 is a specialized, non-proteinogenic amino acid derivative featuring a vinyl substituent on the pyrrolidine nitrogen and a ketone group at the 5-position. This unique molecular architecture makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for constructing complex, nitrogen-containing heterocycles. It is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry, peptide mimetic design, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and for creating peptidomimetics and proline analogs with modified biological activity.
• Organic Synthesis: Acts as a versatile precursor for the synthesis of complex natural products, alkaloids, and other nitrogen-rich heterocyclic frameworks.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies, particularly those involving proline metabolism or proline-specific enzymes.
• Agrochemical Development: Potential use as an intermediate in the synthesis of novel herbicides or plant growth regulators with specific chiral requirements.

Basic Information

Product Name	Proline, 5-Oxo-1-Vinyl-, L- (7Ci,8Ci)
CAS No.	4931-75-3
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	L-1-Vinyl-5-oxoproline; 1-Ethenyl-L-proline-5-carboxylic acid, 5-oxo-; 5-Oxo-L-1-vinylproline; (S)-1-Vinyl-5-oxopyrrolidine-2-carboxylic acid; 1-Vinyl-5-oxo-L-proline; 5-Oxo-1-vinyl-L-proline; 1-Vinyl-5-oxoproline; L-1-Vinyl-5-oxo-2-pyrrolidinecarboxylic acid
EINECS	225-575-5

Quality Control

We supply Proline, 5-Oxo-1-Vinyl-, L- in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.