Description

Acetamide, n-(2,3-Dihydro-2-Oxo-5-Phenyl-1H-1,4-Benzodiazepin-7-Yl)- is a high-purity pharmaceutical intermediate of significant commercial and research importance. This compound is a key building block in the synthesis of complex molecules, offering a critical structural motif for advanced chemical development. It is primarily utilized by the pharmaceutical and fine chemical industries for the research and production of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of benzodiazepine-based active pharmaceutical ingredients (APIs) and other therapeutic compounds.
• Research & Development (R&D): Serves as a key reagent in medicinal chemistry for the design and discovery of new drug candidates, particularly in central nervous system (CNS) research.
• Fine Chemical Synthesis: Used in the production of complex, high-value specialty chemicals requiring the benzodiazepine acetamide moiety.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Employed in university and institutional laboratories for pharmacological studies and synthetic methodology development.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.

Basic Information

Product Name	Acetamide, n-(2,3-Dihydro-2-Oxo-5-Phenyl-1H-1,4-Benzodiazepin-7-Yl)-
CAS No.	4928-03-4
Molecular Formula	C₁₇H₁₅N₃O₂
Molecular Weight	293.32 g/mol
Synonyms	7-Acetamido-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Acetamido-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one; N-(2,3-Dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-7-yl)acetamide; 7-Acetamidodiazepam; 7-Acetamido-5-phenyl-1,4-benzodiazepin-2-one; 4928-03-4; Acetamide, N-(2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-7-yl)-
EINECS	Contact for details

Quality Control

Our Acetamide, n-(2,3-Dihydro-2-Oxo-5-Phenyl-1H-1,4-Benzodiazepin-7-Yl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We can support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.