Description

H-Cys(Ethylcarbamoyl)-Oh is a protected cysteine derivative, specifically an S-ethylcarbamoyl thioether, designed for advanced peptide synthesis and pharmaceutical research. This compound is crucial for introducing cysteine residues into peptide chains while protecting the thiol group from unwanted side reactions, ensuring high-purity and high-yield synthesis. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Peptide Synthesis: A key building block for the controlled incorporation of cysteine in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Serves as a critical intermediate in the production of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Bioconjugation Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other bioconjugates where a protected thiol is required for selective linkage.
• Chemical Biology Research: Employed in the synthesis of modified peptides and proteins for studying structure-activity relationships and biological pathways.
• Protecting Group Strategy: The ethylcarbamoyl group provides stable protection for the cysteine thiol during multi-step synthetic sequences.

Basic Information

Product Name	H-Cys(Ethylcarbamoyl)-Oh
CAS No.	4909-58-4
Molecular Formula	C6H12N2O3S
Molecular Weight	192.24 g/mol
Synonyms	S-(N-Ethylcarbamoyl)cysteine; L-Cysteine, S-[(ethylamino)carbonyl]-; S-Carbamoylethylcysteine; N-[(R)-2-Amino-2-carboxyethyl]-N'-ethylurea; Cysteine S-ethylcarbamate; H-Cys(Etc)-OH; (2R)-2-Amino-3-[(ethylcarbamoyl)sulfanyl]propanoic acid
EINECS	Contact for details

Quality Control

Our H-Cys(Ethylcarbamoyl)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.