Description

Tetrahydro-4-Thioxo-1H-Pyrimidin-2-One is a heterocyclic organic compound featuring a saturated pyrimidine core with a thioxo functional group. This specialized structure makes it a valuable intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or plant growth regulators.
• Chemical Synthesis: Serves as a versatile precursor for creating libraries of thio-substituted heterocyclic compounds for screening.
• Material Science: Potential monomer or additive in the research of specialty polymers with unique properties.
• Academic & Institutional Research: Employed in universities and research institutes for studying reaction mechanisms and heterocyclic chemistry.

Basic Information

Product Name	Tetrahydro-4-Thioxo-1H-Pyrimidin-2-One
CAS No.	4874-14-0
Molecular Formula	C4H6N2OS
Molecular Weight	130.17 g/mol
Synonyms	2-Thioxotetrahydro-4(1H)-pyrimidinone; 2-Thioxohexahydropyrimidin-4-one; 4-Thioxotetrahydro-2(1H)-pyrimidinone; 2-Mercapto-4,5-dihydro-6-hydroxy-4-pyrimidinecarboxylic acid lactam; Tetrahydro-2H-pyrimidine-2,4(1H,3H)-dithione (tautomer); 2-Thiobarbituric acid, dihydro-; Dihydro-2-thiobarbituric acid; 4-Thioxo-1,2,3,4-tetrahydropyrimidin-2-one
EINECS	225-500-5

Quality Control

Our Tetrahydro-4-Thioxo-1H-Pyrimidin-2-One is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.