Description

4-Methyl-2-[(3,4,4-Trifluoro-3-Butenyl)Thio]Pyrimidine is a specialized organofluorine and heterocyclic building block of significant interest in advanced chemical synthesis. Its core value lies in its unique molecular architecture, which combines a pyrimidine ring with a fluorinated thioether side chain, enabling precise modifications in target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating fluorinated motifs to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the fluorine atoms and heterocyclic core can enhance biological activity and environmental persistence.
• Organic Synthesis Building Block: Serves as a versatile precursor in organic chemistry for constructing complex molecules, leveraging its reactive thioether and pyrimidine functionalities.
• Material Science Research: Investigated for potential use in the development of specialty chemicals, such as ligands for catalysis or monomers for advanced polymers.
• Chemical Biology Probe Development: Utilized in academic and industrial research to create molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	4-Methyl-2-[(3,4,4-Trifluoro-3-Butenyl)Thio]Pyrimidine
CAS No.	4871-72-1
Molecular Formula	C9H9F3N2S
Molecular Weight	234.24 g/mol
Synonyms	2-[(3,4,4-Trifluorobut-3-en-1-yl)thio]-4-methylpyrimidine; 4-Methyl-2-((3,4,4-trifluorobut-3-en-1-yl)thio)pyrimidine; 4-Methyl-2-(3,4,4-trifluorobut-3-en-1-ylsulfanyl)pyrimidine; 2-(3,4,4-Trifluorobut-3-enylthio)-4-methylpyrimidine; CAS 4871-72-1
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-[(3,4,4-Trifluoro-3-Butenyl)Thio]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.