Description

Z-Ala-Val-Ome is a protected dipeptide derivative, specifically the methyl ester of the Z-protected alanyl-valine dipeptide. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS) and other advanced organic syntheses, offering precise control over peptide chain assembly. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions developing novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of complex therapeutic peptides and peptidomimetic drugs.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected dipeptide fragment to efficiently elongate peptide chains with high coupling efficiency and minimal racemization.
• Biochemical Research: Employed in the study of enzyme-substrate interactions, protease specificity, and the structure-activity relationships (SAR) of peptides.
• Combinatorial Chemistry: A valuable component in libraries for drug discovery, enabling the rapid generation of diverse peptide-based compounds.
• Academic & Process Development: Used in laboratories for method development, teaching advanced synthetic techniques, and scaling up peptide production processes.
• API Development: Intermediate in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for peptide-based therapies.

Basic Information

Product Name	Z-Ala-Val-Ome
CAS No.	4864-38-4
Molecular Formula	C17H24N2O5
Molecular Weight	336.39 g/mol
Synonyms	Z-Ala-Val-OMe; N-Carbobenzoxy-L-alanyl-L-valine methyl ester; Cbz-L-Ala-L-Val-OMe; Benzyloxycarbonyl-L-alanyl-L-valine methyl ester; (S)-Methyl 2-((S)-2-((benzyloxy)carbonylamino)propanamido)-3-methylbutanoate; Z-A-V-OMe; CBZ-Alanine-Valine Methyl Ester; Nα-Cbz-L-Alanyl-L-valine Methyl Ester
EINECS	Contact for details

Quality Control

Our Z-Ala-Val-Ome is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity, meeting the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.