Description

Potassium 5-Oxo-L-Prolinate is the potassium salt of 5-oxoproline, a key derivative of the amino acid L-proline. This compound serves as a versatile and high-purity building block in advanced synthesis, offering enhanced solubility and stability for demanding applications. It is primarily utilized by the pharmaceutical, nutraceutical, and specialty chemical industries for research, process development, and the manufacture of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical starting material or building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Nutraceutical & Cosmetic Ingredient: Used in the formulation of high-end dietary supplements and skincare products for its potential role in collagen synthesis and cellular protection.
• Biochemical Research: Essential as a substrate or standard in enzymatic studies, metabolic research, and proteomics related to glutathione metabolism and oxidative stress.
• Chiral Synthesis: Serves as a valuable chiral pool reagent for the asymmetric synthesis of complex organic molecules due to its defined stereochemistry.
• Cell Culture Media Component: Employed as a specialized additive in defined media for the cultivation of sensitive cell lines in biopharmaceutical production.

Basic Information

Product Name	Potassium 5-Oxo-L-Prolinate
CAS No.	4810-50-8
Molecular Formula	C5H6KNO3
Molecular Weight	167.20 g/mol
Synonyms	L-Pyroglutamic Acid Potassium Salt; Potassium L-Pyroglutamate; 5-Oxo-L-Proline Potassium Salt; Potassium (S)-2-Pyrrolidone-5-carboxylate; PCA Potassium Salt; L-2-Pyrrolidone-5-carboxylic Acid Potassium Salt; Oxoproline Potassium Salt; Glutamic Acid Lactam Potassium Salt
EINECS	225-376-4

Quality Control

Our Potassium 5-Oxo-L-Prolinate is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-10.0° to -14.0° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition (Sulfated Ash)	30.0% - 35.0%
pH (5% solution)	6.5 - 8.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.