Description

6-Chloro-4-Phenylquinazolin-2(1H)-One is a high-purity, specialized quinazolinone derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and scaffold modification studies within academic and industrial R&D laboratories.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, or insecticides with new modes of action.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Biochemical Tool Compound: May be utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	6-Chloro-4-Phenylquinazolin-2(1H)-One
CAS No.	4797-43-7
Molecular Formula	C14H9ClN2O
Molecular Weight	256.69 g/mol
Synonyms	2(1H)-Quinazolinone, 6-chloro-4-phenyl-; 6-Chloro-4-phenyl-1,2-dihydroquinazolin-2-one; 6-Chloro-4-phenylquinazolin-2-ol; 4-Phenyl-6-chloroquinazolin-2(1H)-one; 6-Chloro-4-phenyl-2(1H)-quinazolinone; 6-Chloro-4-phenyl-1H-quinazolin-2-one
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Phenylquinazolin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.