Description

6-Chloropyrimidin-4(3H)-One is a versatile halogenated pyrimidinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its reactive chlorine atom and the pyrimidinone core, enabling the construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, kinase inhibitors, and other biologically active molecules.
• Agrochemical Synthesis: Precursor in the development of herbicides, fungicides, and plant growth regulators.
• Chemical Research: Valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Used in the preparation of specialty polymers and ligands for metal-organic frameworks (MOFs).
• Dye & Pigment Industry: Intermediate for creating heterocyclic dyes and functional colorants.

Basic Information

Product Name	6-Chloropyrimidin-4(3H)-One
CAS No.	4765-77-9
Molecular Formula	C4H3ClN2O
Molecular Weight	130.53 g/mol
Synonyms	6-Chloro-4-hydroxypyrimidine; 6-Chloro-4(3H)-pyrimidinone; 4-Hydroxy-6-chloropyrimidine; 6-Chloro-4-pyrimidinol; 6-Chloropyrimidin-4-ol; 6-Chloro-1H-pyrimidin-4-one; 6-Chloro-3,4-dihydropyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 6-Chloropyrimidin-4(3H)-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.