Description

3-Methyl-5-Phenyl-7-Chloro-1H-1,4-Benzodiazepine-2(3H)-One is a high-purity benzodiazepine derivative, a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its precise molecular structure, which is critical for producing active pharmaceutical ingredients (APIs) with specific therapeutic profiles. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized central nervous system (CNS) agents and other fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic candidates.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for pharmacological evaluation.

Basic Information

Product Name	3-Methyl-5-Phenyl-7-Chloro-1H-1,4-Benzodiazepine-2(3H)-One
CAS No.	4699-82-5
Molecular Formula	C16H13ClN2O
Molecular Weight	284.74 g/mol
Synonyms	7-Chloro-3-methyl-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one; 7-Chloro-3-methyl-5-phenyl-1,4-benzodiazepin-2-one; 3-Methyl-7-chloro-5-phenyl-1,4-benzodiazepin-2(1H)-one; 4699-82-5; 7-Chloro-3-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1H-1,4-Benzodiazepin-2(3H)-one, 7-chloro-3-methyl-5-phenyl-
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-Phenyl-7-Chloro-1H-1,4-Benzodiazepine-2(3H)-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.