Description

Potassium Pentafluorophenolate is a versatile organofluorine building block and a key reagent in advanced organic synthesis. Its primary value lies in its role as a stable, anionic nucleophile for introducing the highly electron-deficient pentafluorophenyl group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, enabling the development of novel active ingredients and specialty polymers with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the pentafluorophenyl moiety can improve metabolic stability and bioactivity.
• Ligand & Catalyst Preparation: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Polymer & Material Science: Incorporated into monomers for the synthesis of high-performance fluorinated polymers with unique thermal, chemical, and surface properties.
• Cross-Coupling Reactions: Acts as a nucleophile in palladium-catalyzed cross-coupling reactions (e.g., with aryl halides) to form biaryl structures.
• Derivatization Agent: Employed in analytical chemistry for derivatizing compounds to enhance detection in techniques like HPLC or GC-MS.

Basic Information

Product Name	Potassium Pentafluorophenolate
CAS No.	4615-85-4
Molecular Formula	C6F5KO
Molecular Weight	246.16 g/mol
Synonyms	Potassium Pentafluorophenoxide; Pentafluorophenol Potassium Salt; Potassium 2,3,4,5,6-Pentafluorophenolate; Potassium Perfluorophenolate; PFP-K; C6F5OK; Potassium (Pentafluorophenoxy); Pentafluorophenyl Potassium
EINECS	Contact for details

Quality Control

Our Potassium Pentafluorophenolate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data from multiple analytical techniques, such as NMR, HPLC, and Karl Fischer titration, to verify identity, purity, and moisture content. We are committed to meeting the stringent requirements of our global B2B partners in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.